Impact of Nanotechnology on Dental Implants

Autor: Pierre Layrolle, Julie Rozé, Guy Louarn, Sandrine Lavenus, Karthikeyan Subramani
Rok vydání: 2012
Předmět:
Popis: Publisher Summary This chapter elaborates the impact of nanotechnology on dental implants. Recent studies have shown that nanometer-controlled surfaces have a great effect on early events such as the adsorption of proteins, blood clot formation, and cell behaviors occurring upon implantation of dental implants. These early events have an effective impact on the migration, adhesion, and differentiation of mesenchymal stem cells (MSCs). Studies indicate that nanostructured surfaces may control the differentiation pathways into specific lineages and ultimately direct the nature of peri-implant tissues. This chapter begins with a discussion on nanoscale surface modifications. The chapter then elaborates interactions of surface dental implants with blood. Interactions between surfaces and MSCs are also discussed. The chapter reviews the different steps of the interactions between biological fluids, cells, tissues, and surfaces of implants. Recent nanoscale surface modifications and CaP coating technologies of dental implants are discussed. The sequence of biological events in relation to surface properties is related. Mechanisms of interaction with blood, platelets, hematopoietic, and MSCs on the surface of implants are described. The chapter concludes with a discussion on tissue integration.
Databáze: OpenAIRE