Pancreatic perivascular epithelioid cell tumor: A case report with clinicopathological features and a literature review
| Autor: | Na Ta, Ming-Hua Zhang, Gang Jin, Hui Jiang, Kailian Zheng, Jingjing Xu, Xiaoyi Huang, Jianming Zheng |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Perivascular Epithelioid Cell Neoplasms medicine.medical_treatment Case Report Perivascular Epithelioid Cell 03 medical and health sciences Tuberous sclerosis Pancreatectomy 0302 clinical medicine Biopsy Biomarkers Tumor medicine Humans Endoscopic Ultrasound-Guided Fine Needle Aspiration medicine.diagnostic_test business.industry Gastroenterology General Medicine Middle Aged medicine.disease Immunohistochemistry Magnetic Resonance Imaging Pancreatic Neoplasms HMB-45 Treatment Outcome medicine.anatomical_structure 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology Differential diagnosis Tomography X-Ray Computed Pancreas business |
| Zdroj: | World Journal of Gastroenterology. 22:3693 |
| ISSN: | 1007-9327 |
| Popis: | Perivascular epithelioid cell tumor (PEComa) of the pancreas is an unusual tumor deriving from mesenchyma. This paper described a case of pancreatic PEComa, which was initially suspected as neuroendocrine carcinoma by biopsy, and therefore surgical treatment was recommended due to undetermined diagnosis. Examination of the surgical specimen under a microscope showed that the tumor cell's morphology was epithelioid or spindle-shaped, and ranged in a nested pattern. Additionally, these cells had a large extent of acidophilic cytoplasm, no mitotic figures, and expressed HMB-45, melan-p, and smooth muscle actin immunohistochemically. Pathological examination indicated that PEComa originated from the pancreas, but symptoms related to tuberous sclerosis were absent. Since PEComa is extremely rare in the pancreas, it is likely to be ignored in differential diagnosis. In conclusion, our article highlighted the clinicopathological features of PEComa, and we conducted a literature review focusing on PEComa so as to deepen the understanding of this tumor type. |
| Databáze: | OpenAIRE |
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