Ocular fundus abnormalities in cats affected by systemic hypertension: Prevalence, characterization, and outcome of treatment
| Autor: | Valentina Andreani, Giovanni Barsotti, Michele Drigo, Alessandro Cirla |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Moderate to severe medicine.medical_specialty genetic structures Fundus Oculi 040301 veterinary sciences cat Fundus (eye) amlodipine Cat Diseases Gastroenterology 0403 veterinary science 03 medical and health sciences 0302 clinical medicine Retinal Diseases Hypertension prevalence Internal medicine Prevalence medicine Hypertrophic myocardiopathy Animals Prospective Studies Amlodipine ocular fundus abnormalities Antihypertensive Agents CATS General Veterinary business.industry 04 agricultural and veterinary sciences systemic hypertension eye Treatment Outcome Blood pressure Hypertension Cats 030221 ophthalmology & optometry Etiology Female business medicine.drug |
| Popis: | Objectives To determine the prevalence of ocular fundus abnormalities in cats with a diagnosis of systemic hypertension, to characterize the abnormalities observed, and to evaluate ophthalmoscopic evolution during treatment with amlodipine besylate. Animals studied Cats diagnosed as affected by SHP in a 2-year period. Procedures Systemic hypertension was assessed by oscillometric blood pressure measurement, and its etiology was also established. All the cats received an ophthalmic examination, and ocular lesions were classified with a score from 0 (no abnormalities) to 4 (severe abnormalities). All cats received amlodipine besylate by mouth, and those that showed fundus abnormalities were regularly rechecked from 7 to 365 days after diagnosis. Data were statistically analyzed to compare Psys and Pdia with all the variables and to correlate Psys and Pdia with the fundus score. Results A total of 225 cats were enrolled in the study, and the prevalence of fundus abnormalities was 58.6% (21.2%: grade 1; 18.2%: grade 2; 36.4%: grade 3; and 24.2%: grade 4). Systemic hypertension was diagnosed concurrently with chronic renal failure (60.4%), hyperthyroidism (28.9%), both chronic renal failure and hyperthyroidism (7.6%), and hypertrophic myocardiopathy (3.1%). A significant effect of Psys values on the fundus score was detected. Amlodipine therapy improved fundus abnormalities in 50% of cases at the 21-day follow-up. Conclusions This study showed that fundus abnormalities are common in hypertensive cats at the time of the systemic diagnosis, and most of the abnormalities are moderate to severe. Treatment with amlodipine appeared to improve ophthalmic lesions over time. |
| Databáze: | OpenAIRE |
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