Benefits of Zubex beyond glycemic control: Evidence of the antiatherogenic effect
| Autor: | Inayat U Rahman, Muhammad Idrees, Muhammad Iqbal Khan, Mohammad Bashir, Khalil Ur Rahman |
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| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Blood lipids 030209 endocrinology & metabolism 030226 pharmacology & pharmacy Glibenclamide 03 medical and health sciences 0302 clinical medicine Diabetes mellitus Internal medicine medicine Pharmacology (medical) Curcuma Saline Glycemic Liver injury biology business.industry General Medicine biology.organism_classification medicine.disease Streptozotocin Endocrinology Complementary and alternative medicine business medicine.drug |
| Zdroj: | Chinese journal of integrative medicine. |
| ISSN: | 1672-0415 |
| Popis: | To determine the effect of Zubex (aqueous extract of Curcuma longa linn, Iron murakab, Eugenia jambolana, Lin seed or flflax seed, processed egg shell calcium and Asphaltum) on plasma sialic acid (PSA) along with cardiovascular (CV) risk factors in streptozotocin-induced diabetic rats. Thirty male albino rats were divided into groups (1–6) with 5 rats in each group. Group 1 and 2 served as normal control (NC) and diabetic control (DC), respectively, and were given normal saline only. Groups 3–5 were given Zubex in different doses 100–400 mg/(kg day). Group 6 received glibenclamide 600 μg/(kg day) orally as a reference drug. Fasting plasma glucose (FPG) and PSA levels were determined at baseline after every 2 weeks for 10 weeks. The other parameters including blood lipids and hepatic enzymes were determined at baseline and at the end of the study. Finally, the liver was subjected to histological examination. Compared with DC group, Zubex treated groups showed signifificant decline in FPG levels (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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