Circulating miR-150 and miR-342 in plasma are novel potential biomarkers for acute myeloid leukemia

Autor: Philippe Lewalle, Luc Vanhamme, Rabih Badran, Fadwa Berri, Redouane Rouas, Hussein Fayyad-Kazan, Nizar Bitar, Arsène Burny, Nader Hussein, Ahmad Daher, Mohammad Fayyad-Kazan, Bassam Badran, Eva Hamade, Philippe Martiat, Rim ElDirani, Mehdi Najar
Rok vydání: 2013
Předmět:
Oncology
medicine.medical_specialty
Myeloid
Acute myeloblastic leukemia
Tumor Markers
Biological -- blood -- genetics
lcsh:Medicine
Real-Time Polymerase Chain Reaction
General Biochemistry
Genetics and Molecular Biology
Plasma
AML
Micro-RNA
Internal medicine
miR-150
microRNA
Biomarkers
Tumor
medicine
Humans
Leukemia
Myeloid
Acute -- blood -- genetics
Oligonucleotide Array Sequence Analysis
Medicine(all)
Biochemistry
Genetics and Molecular Biology(all)
business.industry
Research
Gene Expression Profiling
lcsh:R
Myeloid leukemia
Cancer
Biomarker
General Medicine
Sciences bio-médicales et agricoles
medicine.disease
Leukemia
Myeloid
Acute
MicroRNAs
Leukemia
medicine.anatomical_structure
ROC Curve
Area Under Curve
Case-Control Studies
Immunology
MicroRNAs -- blood -- genetics
Biomarker (medicine)
business
Zdroj: Journal of translational medicine, 11
Journal of Translational Medicine, Vol 11, Iss 1, p 31 (2013)
Journal of Translational Medicine
ISSN: 1479-5876
Popis: MicroRNAs (miRNAs) are small (19-22-nt) single-stranded noncoding RNA molecules whose deregulation of expression can contribute to human disease including the multistep processes of carcinogenesis in human. Circulating miRNAs are emerging biomarkers in many diseases and cancers such as type 2 diabetes, pulmonary disease, colorectal cancer, and gastric cancer among others; however, defining a plasma miRNA signature in acute myeloblastic leukemia (AML) that could serve as a biomarker for diagnosis or in the follow-up has not been done yet.
Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
info:eu-repo/semantics/published
Databáze: OpenAIRE
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