Advances in Functional Imaging of Differentiated Thyroid Cancer
| Autor: | Livia Lamartina, Martin Schlumberger, Domenico Salvatore, Emanuele Nicolai, Elena Califaretti, Raffaele Ambrosio, Alberto Cuocolo, Carmela Nappi, Désirée Deandreis, Emilia Zampella, Michele Klain |
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| Přispěvatelé: | Klain, Michele, Zampella, Emilia, Nappi, Carmela, Nicolai, Emanuele, Ambrosio, Raffaele, Califaretti, Elena, Lamartina, Livia, Schlumberger, Martin, Deandreis, Désirée, Salvatore, Domenico, Cuocolo, Alberto |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Cancer Research
medicine.medical_specialty Radioiodine uptake diagnosis differentiated thyroid cancer Review Imaging modalities medicine Diagnosis Differentiated thyroid cancer Imaging Radioactive iodine therapy Theragnostic Therapeutic intent Thyroid cancer RC254-282 business.industry theragnostic Fdg uptake Thyroid Neoplasms. Tumors. Oncology. Including cancer and carcinogens imaging medicine.disease radioactive iodine therapy Functional imaging medicine.anatomical_structure Oncology Radiology Radioactive iodine business |
| Zdroj: | Cancers Cancers, Vol 13, Iss 4748, p 4748 (2021) |
| ISSN: | 2072-6694 |
| Popis: | Simple Summary Since the 1940s, radioactive iodine has been used for functional imaging and for treating patients with differentiated thyroid cancer (DTC). During this long-lasting experience, the use of iodine isotopes evolved, especially during the last years due to improved knowledge of thyroid cancer biology and improved performances of imaging tools. The present review summarizes recent advances in the field of functional imaging and theragnostic approach of DTC. Abstract The present review provides a description of recent advances in the field of functional imaging that takes advantage of the functional characteristics of thyroid neoplastic cells (such as radioiodine uptake and FDG uptake) and theragnostic approach of differentiated thyroid cancer (DTC). Physical and biological characteristics of available radiopharmaceuticals and their use with state-of-the-art technologies for diagnosis, treatment, and follow-up of DTC patients are depicted. Radioactive iodine is used mostly with a therapeutic intent, while PET/CT with 18F-FDG emerges as a useful tool in the diagnostic management and complements the use of radioactive iodine. Beyond 18F-FDG PET/CT, other tracers including 124I, 18F-TFB and 68Ga-PSMA, and new methods such as PET/MR, might offer new opportunities in selecting patients with DTC for specific imaging modalities or treatments. |
| Databáze: | OpenAIRE |
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