Histidin as a Mercurial Poisoning Inhibitor

Autor: Anatoli E. Myshkin, Vera S. Khromova
Rok vydání: 2000
Předmět:
Zdroj: Biochemical and Biophysical Research Communications. 273:816-819
ISSN: 0006-291X
DOI: 10.1006/bbrc.2000.3021
Popis: Histidin has been shown to effectively inhibit coagulation of horse oxyhemoglobin (HbO 2 ) modified by mercury(II) ion bound to reactive thiol groups of protein. Kinetic parameters were measured and the histidin-to-mercury binding constant was kinetically estimated. Histidin, as other pharmaceutically acceptable compounds with some mercury-binding capacity, has been suggested to alleviate mercury intoxication conditions.
Databáze: OpenAIRE