Histidin as a Mercurial Poisoning Inhibitor
Autor: | Anatoli E. Myshkin, Vera S. Khromova |
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Rok vydání: | 2000 |
Předmět: | |
Zdroj: | Biochemical and Biophysical Research Communications. 273:816-819 |
ISSN: | 0006-291X |
DOI: | 10.1006/bbrc.2000.3021 |
Popis: | Histidin has been shown to effectively inhibit coagulation of horse oxyhemoglobin (HbO 2 ) modified by mercury(II) ion bound to reactive thiol groups of protein. Kinetic parameters were measured and the histidin-to-mercury binding constant was kinetically estimated. Histidin, as other pharmaceutically acceptable compounds with some mercury-binding capacity, has been suggested to alleviate mercury intoxication conditions. |
Databáze: | OpenAIRE |
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