Recent Progress in the Neurology of Learning
| Autor: | Michael V. Johnston, Karen H. Harum |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
Neurology Transcription Genetic ENCODE Synaptic Transmission Neurobiology Memory Intellectual Disability Neural Pathways Developmental and Educational Psychology medicine Cognitive development Animals Humans Learning Memory disorder Learning memory Memory Disorders Memoria Brain medicine.disease Psychiatry and Mental health Brain Injuries Pediatrics Perinatology and Child Health Learning disability medicine.symptom Psychology Neuroscience |
| Zdroj: | Journal of Developmental & Behavioral Pediatrics. 20:50-56 |
| ISSN: | 0196-206X |
| DOI: | 10.1097/00004703-199902000-00009 |
| Popis: | Memory, the ability to store and retrieve information, is essential for learning in children. Modern neurobiology research is revealing some of the fundamental steps that encode memories within networks of neuronal synaptic connections in the brain. Somewhat different networks store verbal declarative memories and habit or procedural memories. Several biochemical steps convert short-term memories into permanent memories. These changes include activation of neurotransmitter and growth factor receptors, intracellular protein kinases, and nuclear transcription factors that stimulate gene expression of memory proteins. The proteins strengthen synaptic connections and stabilize long-term memories. Genetic defects in those pathways appear to be responsible for several human retardation and learning disability syndromes, including Coffin-Lowry syndrome and neurofibromatosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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