Comparison of articaine and lidocaine for infiltration anaesthesia in patients undergoing bone marrow aspiration and biopsy

Autor: Anna-Maria Kuivalainen, Per H. Rosenberg, Erkki Elonen, Leila Niemi-Murola, Tom Widenius
Rok vydání: 2009
Předmět:
Zdroj: European journal of pain (London, England). 14(2)
ISSN: 1532-2149
Popis: Infiltration anaesthesia with articaine, a local anaesthetic able to penetrate bone, may relieve procedural pain better than lidocaine in bone marrow aspiration and biopsy. This randomised, double-blind study comprised 150 patients with suspected or known haematologic disease. Either articaine 20mg/ml (50 patients), articaine 40mg/ml (49 patients) or lidocaine 20mg/ml (51 patients), all with adrenaline 5mug/ml, was infiltrated in volume of 6ml (sternal manubrium), 8ml (sternal body) or 10ml (iliac crest) 2min before puncture. Numeral rating scale score (median, range) at injection of local anaesthetic was 3.0 (0-10), at bone puncture 2.0 (0-8), at aspiration 3.5 (0-10) and at biopsy (48 patients) 3.0 (0-10). Pre-procedural anxiety, rated on a verbal scale, correlated significantly with experienced pain (P
Databáze: OpenAIRE