Renal Tubular Maximum Reabsorptive Capacity for Phosphate in Patients with Primary Hyperparathyroidism before and after Operation
| Autor: | P. D. Broulik, V. Pacovský |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adenoma
Adult Male medicine.medical_specialty Hypercalcaemia Adolescent Endocrinology Diabetes and Metabolism Parathyroid hormone Absorption Phosphates chemistry.chemical_compound Endocrinology Internal medicine Internal Medicine medicine Humans Aged Parathyroid adenoma Hyperparathyroidism Kidney Phosphorus General Medicine Middle Aged medicine.disease Phosphate Kidney Tubules Parathyroid Neoplasms medicine.anatomical_structure chemistry Renal physiology Calcium Female Primary hyperparathyroidism Glomerular Filtration Rate |
| Zdroj: | Experimental and Clinical Endocrinology & Diabetes. 87:43-47 |
| ISSN: | 1439-3646 0947-7349 |
| DOI: | 10.1055/s-0029-1210521 |
| Popis: | A determination was made of the renal tubular maximum reabsorptive capacity for phosphate (expressed as a function of the glomerular filtrate) in 33 patients with primary hypercalcaemic hyperparathyroidism and 30 control normal subjects. The difference between patients and controls for the maximum renal tubular reabsorptive capacity for phosphate (patients 0.526 +/- 0.16 mmol/l, controls 1.010 +/- 0.14 mmol/l) was highly significant (p less than 0.001). Successful removal of a single parathyroid adenoma in 19 patients was associated with a highly significant rise in the renal tubular maximum reabsorptive capacity for phosphate (1.005 +/- 0.21 mmol/l, p less than 0.001). We did not find any correlation between the renal tubular maximum reabsorptive capacity for phosphate and serum immunoreactive PTH level. Low renal tubular maximum reabsorptive capacity for phosphate in the presence of hypercalcaemia is highly suggestive of primary hyperparathyroidism. |
| Databáze: | OpenAIRE |
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