Topical anaesthesia of gingival mucosa by 5% eutectic mixture of lignocaine and prilocaine or by 10% lignocaine spray
| Autor: | Numminen M, Haasio J, P.H. Rosenberg, Jokinen T |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Time Factors Lidocaine Dose medicine.drug_class Administration Topical Gingiva Dentistry Absorption (skin) Prilocaine Dosage form Random Allocation Threshold of pain medicine Humans Anesthetics Local Lidocaine Prilocaine Drug Combination Eutectic system business.industry Local anesthetic Mouth Mucosa Drug Combinations Otorhinolaryngology Anesthesia Sensory Thresholds Surgery Female Oral Surgery business medicine.drug |
| Zdroj: | The British journal of oralmaxillofacial surgery. 28(2) |
| ISSN: | 0266-4356 |
| Popis: | The analgesic effect of topical application of local anaesthetics on the gingival mucosa and the absorption of the local anaesthetics into the blood were investigated in healthy volunteers by using a 5% eutectic mixture of the local anaesthetics lignocaine (100 mg) and prilocaine (100 mg) plus emulsifier (EMLA®) or 10% lignocaine (200 mg) spray (Xylocain®). The pain threshold on labial gingiva was measured by using the stimulator of an EMG-apparatus and a pair of stimulating electrodes, specially constructed for this purpose. There were no differences between the two methods in producing analgesia which was at its maximum in 13 to 14 minutes, on average. Sensation of the gingiva (pain thresholds), had usually returned to normal within 30 minutes. In the dosages used, the absorption of the local anaesthetics was more rapid after the mixture application than after spray application. No toxic reactions occurred. |
| Databáze: | OpenAIRE |
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