Influenza A(H5N1) viruses with A(H9N2) single gene (matrix or PB1) reassortment isolated from Cambodian live bird markets
Autor: | Paul F. Horwood, Andrew R. Greenhill, Aeron C. Hurt, Sokhoun Yann, San Sorn, Songha Tok, Davun Holl, Annika Suttie, Srey Viseth Horm, Yi-Mo Deng, Erik A. Karlsson, Philippe Dussart, Sothyra Tum, Ian G. Barr |
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Přispěvatelé: | Unité de Virologie / Virology Unit [Phnom Penh], Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Federation University [Churchill, Australia], The Peter Doherty Institute for Infection and Immunity [Melbourne], The Royal Melbourne Hospital-University of Melbourne, Ministry of Agriculture, Forestry and Fisheries [Cambodia], James Cook University (JCU), This publication is the result of work conducted under a cooperative agreement with the Office of the Assistant Secretary for Preparedness and Response in the U.S. Department of Health and Human Services (HHS), grant number IDSEP140020-01-00. Its contents and conclusions are solely the responsibility of the authors and do not represent the official views of HHS. The study was also funded, in part, by the US Agency for International Development (grant No. AID-442-G-14-00005). Annika Suttie is funded by an Australian Government Research Training Program Scholarship and a Faculty of Science and Technology Research Scholarship from Federation University. The Melbourne WHO Collaborating Centre for Reference and Research on Influenza is supported by the Australian Government Department of Health. |
Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
animal diseases viruses Reassortment Gene Expression medicine.disease_cause A(H5N1) MESH: Ducks Influenza A Virus H9N2 Subtype MESH: Animals MESH: Phylogeny Clade Phylogeny 2. Zero hunger Live bird markets MESH: Chickens virus diseases 3. Good health MESH: Reassortant Viruses Ducks [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology Epidemiological Monitoring Cambodia Reassortant Viruses MESH: Gene Expression MESH: Influenza A Virus H5N1 Subtype Single gene MESH: Poultry Diseases Biology Viral Matrix Proteins Viral Proteins 03 medical and health sciences MESH: Influenza in Birds Phylogenetics Virology medicine Animals Gene Poultry Diseases MESH: Viral Matrix Proteins Viral matrix protein Influenza A Virus H5N1 Subtype MESH: Cambodia MESH: Viral Proteins Influenza Influenza A virus subtype H5N1 MESH: Influenza A Virus H9N2 Subtype 030104 developmental biology Influenza in Birds MESH: Epidemiological Monitoring Chickens A(H9N2) |
Zdroj: | Virology Virology, Elsevier, 2018, 523, pp.22-26. ⟨10.1016/j.virol.2018.07.028⟩ |
ISSN: | 0042-6822 1096-0341 |
Popis: | International audience; Live bird market surveillance for avian influenza viruses in Cambodia in 2015 has led to the detection of two 7:1 reassortant influenza A(H5N1) clade 2.3.2.1c viruses. These reassortant strains, designated A/duck/Cambodia/ Z564W35M1/2015 and A/chicken/Cambodia/Z850W49M1/2015, both contained a single gene (PB1 and matrix gene, respectively) from concurrently circulating A(H9N2) influenza viruses. All other viral genes from both isolates clustered with A(H5N1) clade 2.3.2.1 viruses. Continued and prolonged co-circulation of influenza A(H5N1) and A(H9N2) viruses in Cambodian live bird markets may present a risk for the emergence of novel influenza reassortant viruses with negative agricultural and/or public health implications. |
Databáze: | OpenAIRE |
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