Myocardial extracellular volume expansion in patients with hypertension
| Autor: | Ron Blankstein, Ciaran J. McMullan, François-Pierre Mongeon, Ravi V. Shah, Otavio R. Coelho-Filho, Bobby Heydari, Siddique Abbasi, Eri Watanabe, Michael Jerosch-Herold, Raymond Y. Kwong, Tomas G. Neilan |
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| Jazyk: | angličtina |
| Předmět: |
lcsh:Diseases of the circulatory (Cardiovascular) system
Pediatrics medicine.medical_specialty 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Internal medicine Extracellular fluid Medicine Radiology Nuclear Medicine and imaging Mass index In patient Adverse effect Angiology Medicine(all) Radiological and Ultrasound Technology business.industry Hazard ratio medicine.disease lcsh:RC666-701 Heart failure Cardiology cardiovascular system Oral Presentation Myocardial fibrosis Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Cardiovascular Magnetic Resonance Journal of Cardiovascular Magnetic Resonance, Vol 15, Iss Suppl 1, p O110 (2013) |
| ISSN: | 1532-429X |
| DOI: | 10.1186/1532-429x-15-s1-o110 |
| Popis: | Background Hypertension is associated with the development of myocardial fibrosis with a subsequent increase in the myo- cardial extracellular volume (ECV). T1 measurements pre and post a contrast cardiac magnetic resonance (CMR) study provide a robust non-invasive method for quantifi- cation of the ECV. We aimed to determine whether the CMR-derived ECV can differentiate healthy volunteers from patients with systemic arterial hypertension. Methods of 61±6%. In comparison to healthy controls, patients with hypertension had elevated LV volumes, LV mass, and left atrial volumes. The ECV was elevated in patients with hypertension as compared to healthy controls (hyperten- sion vs. healthy controls, 0.34±0.03 vs. 0.29±0.03, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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