Desire for children among male survivors of childhood cancer
Autor: | Claessens, J.J.M., Penson, A., Bronkhorst, E.M., Kremer, L.C.M., Dulmen-den Broeder, E. van, Heiden-van der Loo, M., Tissing, W.J.E., Pal, H.J. van der, Blijlevens, N.M.A., Heuvel-Eibrink, M.M. van den, Versluys, A.B., Bresters, D., Ronckers, C.M., Walraven, I., Beerendonk, C.C., Loonen, J.J. |
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Přispěvatelé: | Pediatrics, CCA - Cancer Treatment and quality of life, Amsterdam Reproduction & Development (AR&D) |
Jazyk: | angličtina |
Rok vydání: | 2023 |
Předmět: |
Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]
Cancer Research All institutes and research themes of the Radboud University Medical Center Oncology Urological cancers Radboud Institute for Health Sciences [Radboudumc 15] Women's cancers Radboud Institute for Health Sciences [Radboudumc 17] Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18] Rare cancers Radboud Institute for Health Sciences [Radboudumc 9] |
Zdroj: | Dutch LATER study group 2023, ' Desire for children among male survivors of childhood cancer : A DCCSS LATER study ', Cancer, vol. 129, no. 9, pp. 1432-1442 . https://doi.org/10.1002/cncr.34685 Cancer, 129, 9, pp. 1432-1442 Cancer, 129, 1432-1442 Cancer, 129(9), 1432-1442. John Wiley and Sons Inc. |
ISSN: | 0008-543X |
DOI: | 10.1002/cncr.34685 |
Popis: | Contains fulltext : 291886.pdf (Publisher’s version ) (Open Access) BACKGROUND: Knowledge of the desire for children among childhood cancer survivors (CCSs) is scarce. This study evaluated the desire for children in male CCSs in comparison with male siblings. METHODS: A nationwide cohort study was conducted as part of the Dutch Childhood Cancer Survivor Study LATER study: 1317 male CCSs and 407 male sibling controls completed a questionnaire addressing the desire for children. Logistic regression analyses were used to explore the independent association between survivorship status and the desire for children. Furthermore, additional analyses were performed to identify which cancer-related factors were associated with the desire for children in male CCSs. RESULTS: After adjustments for the age at assessment, the percentage of men who had a desire for children was significantly lower among CCSs compared with the siblings (74% vs. 82%; odds ratio [OR], 0.61; 95% CI, 0.46-0.82; p = .001). The association between survivorship status and the desire for children was attenuated after adjustments for marital status, level of education, and employment status (OR, 0.83; 95% CI, 0.61-1.14; p = .250). The percentage of men who had an unfulfilled desire for children remained significantly higher among CCSs compared with the siblings after adjustments for sociodemographic factors (25% vs. 7%; OR, 5.14; 95% CI, 2.48-10.64; p |
Databáze: | OpenAIRE |
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