Desire for children among male survivors of childhood cancer

Autor: Claessens, J.J.M., Penson, A., Bronkhorst, E.M., Kremer, L.C.M., Dulmen-den Broeder, E. van, Heiden-van der Loo, M., Tissing, W.J.E., Pal, H.J. van der, Blijlevens, N.M.A., Heuvel-Eibrink, M.M. van den, Versluys, A.B., Bresters, D., Ronckers, C.M., Walraven, I., Beerendonk, C.C., Loonen, J.J.
Přispěvatelé: Pediatrics, CCA - Cancer Treatment and quality of life, Amsterdam Reproduction & Development (AR&D)
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Dutch LATER study group 2023, ' Desire for children among male survivors of childhood cancer : A DCCSS LATER study ', Cancer, vol. 129, no. 9, pp. 1432-1442 . https://doi.org/10.1002/cncr.34685
Cancer, 129, 9, pp. 1432-1442
Cancer, 129, 1432-1442
Cancer, 129(9), 1432-1442. John Wiley and Sons Inc.
ISSN: 0008-543X
DOI: 10.1002/cncr.34685
Popis: Contains fulltext : 291886.pdf (Publisher’s version ) (Open Access) BACKGROUND: Knowledge of the desire for children among childhood cancer survivors (CCSs) is scarce. This study evaluated the desire for children in male CCSs in comparison with male siblings. METHODS: A nationwide cohort study was conducted as part of the Dutch Childhood Cancer Survivor Study LATER study: 1317 male CCSs and 407 male sibling controls completed a questionnaire addressing the desire for children. Logistic regression analyses were used to explore the independent association between survivorship status and the desire for children. Furthermore, additional analyses were performed to identify which cancer-related factors were associated with the desire for children in male CCSs. RESULTS: After adjustments for the age at assessment, the percentage of men who had a desire for children was significantly lower among CCSs compared with the siblings (74% vs. 82%; odds ratio [OR], 0.61; 95% CI, 0.46-0.82; p = .001). The association between survivorship status and the desire for children was attenuated after adjustments for marital status, level of education, and employment status (OR, 0.83; 95% CI, 0.61-1.14; p = .250). The percentage of men who had an unfulfilled desire for children remained significantly higher among CCSs compared with the siblings after adjustments for sociodemographic factors (25% vs. 7%; OR, 5.14; 95% CI, 2.48-10.64; p
Databáze: OpenAIRE