Review on Opioid Addiction and Therapy

Autor: Vaishali Shinde, N.V. Thorat
Jazyk: angličtina
Rok vydání: 2022
Předmět:
DOI: 10.5281/zenodo.7467643
Popis: The primary pharmacotherapies for treating opioid addiction are covered in this article. Treatment options include quick detoxification methods, buprenorphine, adrenergic agonists such clonidine and lofexidine, and detoxification utilising tapering methadone. Methadone is most frequently used in opioid maintenance therapy (OMT). Also mentioned is OMT using additional opioid agonists, buprenorphine, or buprenorphine with naloxone. The usage of oral and sustained-release naltrexone formulations for relapse prevention as well as the opioid antagonists naloxone (for the treatment of intoxication and overdose) and naltrexone are also taken into consideration. Although recent discoveries about the neuroscience of addiction may result in the creation of novel pharmaceutical medicines for the management of addictive diseases, improving the efficacy of currently available therapies remains a significant problem. For opioid addiction, pharmacotherapy alone is frequently insufficient; a full course of treatment should also include efficient psychological support or other therapies. The most successful approach to treating opioid addiction involves combining pharmacotherapies with patient-specific psychosocial support techniques.
Databáze: OpenAIRE