Determination of subclinical atherosclerosis in plaque type psoriasis patients without traditional risk factors for atherosclerosis

Autor: Emre Refik Altekin, Ibrahim Basarici, Ibrahim Demir, Serkan Koc, Atakan Yanikoglu, Erkan Alpsoy, Mustafa Serkan Karakaş
Přispěvatelé: Altekin, E.R., Department of Cardiology, Akdeniz University Faculty of Medicine, Antalya, Turkey -- Koç, S., Department of Cardiology, Agri State Hospital, Agri, Turkey -- Karakaş, M.S., Department of Cardiology, Nigde State Hospital, Nigde, Turkey -- Yanikoglu, A., Department of Cardiology, Akdeniz University Faculty of Medicine, Antalya, Turkey -- Başarici, I., Department of Cardiology, Akdeniz University Faculty of Medicine, Antalya, Turkey -- Demir, I., Department of Cardiology, Akdeniz University Faculty of Medicine, Antalya, Turkey -- Alpsoy, E., Department of Dermatology and Venorology, Akdeniz University Faculty of Medicine, Antalya, Turkey, 0-Belirlenecek
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Adult
Male
medicine.medical_specialty
Psoriasis/blood/epidemiology
Pulse Wave Analysis
Systemic inflammation
Carotid Intima-Media Thickness
Severity of Illness Index
Lipid metabolism disorders
Hemoglobins
Leukocyte Count
Carotid arteries/pathology/ultrasonography
Psoriasis Area and Severity Index
Psoriasis
Internal medicine
medicine
Humans
Platelet activation
Pulse
Pulse wave velocity
Triglycerides
business.industry
Cholesterol
HDL
ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS
Case-control study
Cholesterol
LDL
Middle Aged
C-Reactive protein
medicine.disease
Atherosclerosis
ComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMS
Cholesterol
ComputingMethodologies_PATTERNRECOGNITION
Intima-media thickness
Risk factors
Rheumatoid arthritis
Case-Control Studies
cardiovascular system
Cardiology
Female
medicine.symptom
InformationSystems_MISCELLANEOUS
Atherosclerosis/epidemiology
Cardiology and Cardiovascular Medicine
business
Popis: PubMed ID: 23363939
Objectives: Systemic inflammation plays an important role in the pathogenesis of atherosclerosis in psoriasis patients. Therefore, persistent skin inflammation in psoriasis patients may contribute to the development of premature atherosclerosis, as it occurs in rheumatoid arthritis and systemic lupus erythematosus. We aimed to evaluate the relationship between subclinical atherosclerosis and psoriasis by using pulse wave velocity (PWV) and the measurement of carotid intima media thickness (CIMT) in psoriatic patients. Study design: Fifty-seven plaque-type psoriasis patients (31 males, 26 females; mean age 41±10.8 years) and 60 healthy individuals (32 males, 28 females; mean age 40±9.4 years) were included. Atherosclerotic risk factors were excluded in both of the groups. Demographic, bio-chemical data, psoriasis area and severity index (PASI) score of the psoriasis group, and disease duration were recorded. Carotid-femoral artery PWV and CIMT values were compared. Results: PWV, and the maximum and average CIMT values of psoriasis patients were higher than those of the healthy group (PWV: 7.04±1.1 m/sn vs. 6.03±0.61 m/sn, p
Databáze: OpenAIRE
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