Liver function in septic shock
| Autor: | A K Foulis, J G Banks, R N Macsween, I M Ledingham |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Male
medicine.medical_specialty Poor prognosis Cholestasis Intrahepatic Gastroenterology Pathology and Forensic Medicine Liver Function Tests Cholestasis Internal medicine Humans Medicine Retrospective Studies medicine.diagnostic_test business.industry Septic shock Retrospective cohort study General Medicine Middle Aged medicine.disease Shock Septic Surgery Liver Shock (circulatory) Etiology Female Liver function medicine.symptom business Liver function tests Research Article |
| Zdroj: | Journal of Clinical Pathology. 35:1249-1252 |
| ISSN: | 0021-9746 |
| DOI: | 10.1136/jcp.35.11.1249 |
| Popis: | Serum liver function tests were estimated in 57 patients admitted to an Intensive Therapy Unit (ITU) with a diagnosis of septic shock. Following an initial biochemical disturbance, persisting hyperbilirubinaemia was associated with a poor prognosis. Post-mortem liver histology in 22 patients showed varying degrees of non-specific reactive change, venous congestion, ischaemic necrosis, fatty change and intrahepatic cholestasis in 16 cases. In the remaining six cases there was moderately severe cholestasis with inspissated bile in the cholangioles. The possible aetiology of the observed cholestasis is discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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