A new protocol of programmed stimulation for assessment of predisposition to spontaneous ventricular arrhythmias*
| Autor: | Paul A. Russell, David V. Cody, Alistair A. Young, David Richards, Alan Robert Denniss, John B. Uther |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Adult
Tachycardia medicine.medical_specialty Heart Ventricles Myocardial Infarction Diastole Stimulation Internal medicine medicine Humans cardiovascular diseases Myocardial infarction Aged business.industry Cardiac arrhythmia Arrhythmias Cardiac Heart Middle Aged Prognosis medicine.disease Electric Stimulation Intensity (physics) Anesthesia Ventricular Fibrillation Ventricular fibrillation cardiovascular system Cardiology Myocardial infarction complications Disease Susceptibility medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | European Heart Journal. 4:376-382 |
| ISSN: | 1522-9645 0195-668X |
| DOI: | 10.1093/oxfordjournals.eurheartj.a061483 |
| Popis: | We have devised a simple method for identifying predisposition to spontaneous sustained ventricular fibrillation (VF) and tachycardia (VT). A standardized protocol of programmed stimulation was applied to 111 control subjects without ventricular disease and with no history of VF or VT (Group I) and to 27 patients with previous myocardial infarction and documented spontaneous (in the absence of evidence of further acute myocardial ischaemia) VF or VT (Group II). The stimulation protocol consisted of single and paired ventricular extra stimuli introduced during ventricular drive at the right ventricular apex and outflow tract, at twice diastolic threshold current intensity and at 20 mA. None of the Group I subjects exhibited VF or sustained (more than 10 s) VT. In contrast sustained arrhythmias were induced in 24 (89%) of Group II patients. We conclude: In our study population, initiation of a sustained ventricular tachyarrhythmia at programmed stimulation was both a sensitive (89%) and specific (100%) indicator for predisposition to spontaneous VF and VT. |
| Databáze: | OpenAIRE |
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