| Autor: |
N Yao, Z Zhang, L Yu, R Hazarika, C Yu, H Jang, LM Smith, J Ton, L Liu, J Stachowicz, TBH Reusch, RJ Schmitz, F Johannes |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
bioRxiv |
| DOI: |
10.1101/2023.03.15.532766 |
| Popis: |
Molecular clocks are the basis for dating the divergence between lineages over macro-evolutionary timescales (~105-108years). However, classical DNA-based clocks tick too slowly to inform us about the recent past. Here, we demonstrate that stochastic DNA methylation changes at a subset of cytosines in plant genomes possess a clock-like behavior. This ‘epimutation-clock’ is orders of magnitude faster than DNA-based clocks and enables phylogenetic explorations on a scale of years to centuries. We show experimentally that epimutation-clocks recapitulate known topologies and branching times of intra-species phylogenetic trees in the selfing plantA. thalianaand the clonal seagrassZ. marina, which represent two major modes of plant reproduction. This discovery will open new possibilities for high-resolution temporal studies of plant biodiversity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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