Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children

Autor:	Domenico Corica, Simona Santucci, Giuseppina Salzano, Filippo De Luca, Tommaso Aversa, Giuseppina Zirilli, Mariella Valenzise
Rok vydání:	2017
Předmět:	Male Thyroid function endocrine system medicine.medical_specialty Pediatrics Adolescent Chromosomopathies endocrine system diseases Turner syndrome Thyroid Gland Thyrotropin 030209 endocrinology & metabolism Thyroiditis 03 medical and health sciences Down’s syndrome 0302 clinical medicine Hypothyroidism 030225 pediatrics Internal medicine medicine Humans Child Subclinical infection Chromosomopathies Down’s syndrome Hashimoto’s thyroiditis Thyroid function Thyroid status Turner syndrome Pediatrics Perinatology and Child Health business.industry Thyroid Disease progression Hashimoto’s thyroiditis Thyroid status Perinatology and Child Health medicine.disease Natural history Endocrinology medicine.anatomical_structure Commentary Disease Progression Etiology Female business
Zdroj:	Italian Journal of Pediatrics
ISSN:	1824-7288
Popis:	Aim of this commentary is to report the most recent views about natural history of subclinical hypothyroidism (SH) according to the different etiologies. In children with idiopathic SH the natural evolution is often favourable, with a high percentage of cases reverting to euthyroidism or remaining SH even after a prolonged follow-up. By contrast, the risk of a significant deterioration of thyroid status is distinctly higher in the SH children with Hashimoto's thyroiditis (HT). This risk is even higher in the cases with both HT-related SH and chromosomal abnormalities, such as Turner or Down's syndrome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9438fc7b4a8b2e860a2b7b7d80226b52 https://doi.org/10.1186/s13052-016-0322-z Zobrazit plný text záznamu Plný text ve formátu PDF