Design of enzymatic cascade processes for the production of low-priced chemicals
| Autor: | Ángela Viviana Ruales-Salcedo, Juan C. Higuita, Javier Fontalvo, John M. Woodley |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
010402 general chemistry
01 natural sciences Gluconates Lignin General Biochemistry Genetics and Molecular Biology Biocatalytic reactions Glucose Oxidase Lactones Reaction modules Production (economics) Cellulases Humans Computer Simulation Waste Products Models Statistical 010405 organic chemistry beta-Glucosidase Temperature Hydrogen-Ion Concentration Catalase 0104 chemical sciences Kinetics Glucose Metabolic Engineering Cascade Biocatalysis Fermentation Multi-enzymatic cascade Biochemical engineering Biocatalyst |
| Zdroj: | Ruales-Salcedo, A V, Higuita, J C, Fontalvo, J & Woodley, J M 2019, ' Design of enzymatic cascade processes for the production of low-priced chemicals ', Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences, vol. 74, no. 3-4, pp. 77-84 . https://doi.org/10.1515/znc-2018-0190 |
| Popis: | While the application of enzymes to synthetic and industrial problems continues to grow, the major development today is focused on multi-enzymatic cascades. Such systems are particularly attractive, because many commercially available enzymes operate under relatively similar operating conditions. This opens the possibility of one-pot operation with multiple enzymes in a single reactor. In this paper the concept of modules is introduced whereby groups of enzymes are combined in modules, each operating in a single reactor, but with the option of various operating strategies to avoid any complications of nonproductive interactions between the enzymes, substrates or products in a given reactor. In this paper the selection of modules is illustrated using the synthesis of the bulk chemical, gluconic acid, from lignocellulosic waste. |
| Databáze: | OpenAIRE |
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