Effects of adrenalectomy on open-field behavior in rats

Autor: Richard A. Rawson, Justin M. Joffe, James A. Mulick
Rok vydání: 1972
Předmět:
Zdroj: Hormones and Behavior. 3:87-96
ISSN: 0018-506X
Popis: Two experiments investigated the effects of adrenalectomy (Adx) on open-field defecation and activity in Long-Evans hooded rats. In the first it was found that Adx females defecated significantly more than unoperated controls. In Expt 2 both males and females were included, as well as the appropriate sham-operated groups. Adrenalectomy significantly increased defecation in both sexes as compared to either sham-operated or intact controls. The significantly lower home-cage defecation of Adx groups appears to rule out a general increase in defecation as an explanation of this effect. Adx rats were also significantly less active than controls on Days 3 and 4 of testing as a result of a greater drop in activity over the four days of testing. The defecation scores and activity pattern displayed by Adx animals is characteristic of more “emotional” rats.
Databáze: OpenAIRE