BY-COVID - WP5 - Baseline Use Case: COVID-19 vaccine effectiveness assessment - Study protocol

Autor: Meurisse, Marjan, Van Goethem, Nina, Estupiñán-Romero, Francisco, González-Galindo, Javier, Royo-Sierra, Santiago, Martínez-Lizaga, Natalia, Bernal-Delgado, Enrique
Jazyk: angličtina
Rok vydání: 2023
Předmět:
DOI: 10.5281/zenodo.7560731
Popis: This publication corresponds to the studyprotocolof the Baseline Use Case proposed in T.5.2 (WP5) in theBY-COVID projecton“SARS-CoV-2Vaccineeffectiveness in preventing SARS-CoV-2 infection.” Research question: We aim to investigate the real-world effectiveness of SARS-CoV-2 primary vaccination as compared to partial or no vaccination in preventing SARS-CoV-2 infection in virtually all resident populations spanning different countries. Study design: An observational retrospective longitudinal (cohort) study using routinely collected social, health and care data from several countries/regions in Europe. We have designed the observational study to emulate a hypothetical Target Trial (TT) of the causal effect of SARS-CoV-2 vaccination programs in preventing SARS-CoV-2 infections. Fileincluded in this publication: Study protocol (PDF): The protocol provides a work plan, including details on the research team, study rationale, methodology, and ethical aspects. The implementation of this study is supported by supplementary documents including a causal model (DAG), a common data model specification, and a simulated dataset following the specification of the common data model. This information is available athttps://doi.org/10.5281/zenodo.6913045.  
Databáze: OpenAIRE