Assessment of risk-independent follow-up to detect asymptomatic recurrence after curative resection of colorectal cancer

Autor: Werner Kirchmayr, Matthias Zitt, Raimund Margreiter, Gilbert Mühlmann, Helmut Weiss, Alexander Klaus, Dietmar Öfner, Michael Oberwalder, Reinhold Kafka-Ritsch
Rok vydání: 2006
Předmět:
Zdroj: Langenbeck's Archives of Surgery. 391:369-375
ISSN: 1435-2451
1435-2443
DOI: 10.1007/s00423-006-0045-5
Popis: Colorectal cancer is one of the leading causes of cancer death. We analyzed the value of standardized, risk-independent postoperative surveillance. Between 1995 and 2001, 564 patients with colorectal cancer underwent standardized oncologic resection. One hundred thirty-four were unable to take part in the surveillance program, while 430 patients were grouped as follows: group I (n=272, risk-independent follow-up), group II (n=113, follow-up at other departments), and group III (n=45, no follow-up). The 5-year cancer-specific survival rate for UICC III and IV was significantly higher in group I (87%) as compared to group II (35%). In group I, the 5-year disease-free survival rate was 70%. Cancer recurrence occurred at mean 17 (±12) months after colorectal resection and yielded a 5-year survival rate of 63%. Reresection was performed in 17 (35%) patients, of whom ten remained disease-free (5-year survival rate, 91%). The money spent for one patient’s 5-year follow-up was 1665. A standardized, risk-independent follow-up program allows early diagnosis of asymptomatic recurrence of colorectal cancer. Reresection improves the 5-year survival rate in this setting.
Databáze: OpenAIRE