Genital Human Papilloma Virus Infection in Males. A Clinico-Pathologic Study
| Autor: | S. Pilotti, Bandieramonte G, De Palo G, Franco Rilke, R. Koronel, B. Stefanon |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Penile Diseases Adolescent Uterine Cervical Neoplasms 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine Humans Papillomaviridae Glans Aged Subclinical infection Contraceptive Devices Male Intraepithelial neoplasia Vulvar Neoplasms biology business.industry HPV infection Sexually Transmitted Diseases Viral General Medicine Middle Aged medicine.disease Vulvar intraepithelial neoplasia biology.organism_classification Dermatology Virology Tumor Virus Infections medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Penile Intraepithelial Neoplasia Female business Penis Follow-Up Studies |
| Zdroj: | Tumori Journal. 77:76-82 |
| ISSN: | 2038-2529 0300-8916 |
| DOI: | 10.1177/030089169107700118 |
| Popis: | From March 1987 to December 1988, 402 male sexual partners of 317 women with human papilloma virus (HPV) infection of the lower genital tract and 85 with HPV-associated cervical and/or vulvar intraepithelial neoplasia (CIN and/or VIN) were submitted to clinical examination and peniscopy. The latter was performed at a 6-15 X magnification after a 3 min exposure to 5% acetic acid solution. Visible lesions were biopsied. Thirty-one patients had clinical evidence of HPV infection in the glans, penile shaft or urethra, and 222 had peniscopic evidence of subclinical aceto-white lesions. Of 31 patients with clinical lesions, 11 showed also aceto-white subclinical lesions. Of 253 peniscopically positive males, 237 were biopsied and 191 of these were histologically ascertained. Three patients had penile intraepithelial neoplasia, one with clinical appearance of a Buschke-Löwenstein tumor. The incidence of HPV infection in male sexual partners of women affected by HPV infection of the lower genital tract associated or not with intraepithelial neoplasia is lower than expected. However, clinically negative males should not be considered disease free; in fact, 12 patients, negative at the first examination, showed histological evidence of HPV infection at subsequent controls. Therefore, follow-up of at least 6 months should be allowed to Identify HPV bearing males. The reported low frequency of HPV infection may be due to the fact that the males may harbour the virus in the urethra, prostate or seminal vesicles or penis without any clinical evidence of disease. Although research for HPV-DNA in intraurethral and penile scraping material might be useful for diagnosis, peniscopy with a 5% acetic acid application remains the clinical test for evaluating HPV Infection in males. The importance of peniscopy should be viewed with respect to the prevention of infection or reinfection of the female sexual partners, in addition to the specific diagnostic purpose in male patients. |
| Databáze: | OpenAIRE |
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