Translocation involving chromosome 22 in Ewing's Sarcoma. A cytogenetic study of four fresh tumors
Autor: | Jean-Michel Zucker, Alain Aurias, André Mazabraud, D. Buffe, C. Rimbaut |
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Rok vydání: | 1984 |
Předmět: |
Chromosomes
Human 6-12 and X Cancer Research Ewing's sarcoma Aneuploidy Chromosomal translocation Karyotype Sarcoma Ewing Biology medicine.disease Malignancy Virology Translocation Genetic Chromosome Banding Karyotyping Chromosomes Human 21-22 and Y Genetics medicine Cancer research Humans Sarcoma Neoplasm Metastasis Molecular Biology Chromosome 22 |
Zdroj: | Cancer Genetics and Cytogenetics. 12:21-25 |
ISSN: | 0165-4608 |
Popis: | Ewing's sarcoma was described in 1921 by James Ewing as a diffuse endothelioma of bone and, for some time, was believed to be an undifferentiated type of Parker's sarcoma. At present, these two entities are thought to be distinct, the macroscopic and microscopic aspects of Ewing's sarcoma being very characteristic, although the exact cell type of this tumor remains unknown. This has lead many workers to study this sarcoma in order to recognize its origin. We thought it of interest to carry out cytogenetic investigations of our cases of Ewing's sarcoma, since very few chromosomal data on this malignancy exist in the literature [1-3]. |
Databáze: | OpenAIRE |
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