Multicellular Vascularized Engineered Tissues through User-Programmable Biomaterial Photodegradation
| Autor: | Christopher K. Arakawa, Ying Zheng, Cole A. DeForest, Barry A. Badeau |
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| Rok vydání: | 2017 |
| Předmět: |
Materials science
Microfluidics Nanotechnology Biocompatible Materials 02 engineering and technology 010402 general chemistry Multiphoton lithography 01 natural sciences Article Tissue engineering Humans General Materials Science Microchannel Photolysis Tissue Engineering Mechanical Engineering Biomaterial Hydrogels 021001 nanoscience & nanotechnology Cell function 0104 chemical sciences Multicellular organism Mechanics of Materials Self-healing hydrogels 0210 nano-technology |
| Zdroj: | Advanced materials (Deerfield Beach, Fla.). 29(37) |
| ISSN: | 1521-4095 |
| Popis: | A photodegradable material-based approach to generate endothelialized 3D vascular networks within cell-laden hydrogel biomaterials is introduced. Exploiting multiphoton lithography, microchannel networks spanning nearly all size scales of native human vasculature are readily generated with unprecedented user-defined 4D control. Intraluminal channel architectures of synthetic vessels are fully customizable, providing new opportunities for next-generation microfluidics and directed cell function. |
| Databáze: | OpenAIRE |
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