Enantioselective Dearomatization of Indoles by an Azoalkene-Enabled (3+2) Reaction: Access to Pyrroloindolines

Autor:	Yixin Lu, Xiwen Tang, Yildiz Tasdan, Guang-Jian Mei
Rok vydání:	2019
Předmět:	Indole test 010405 organic chemistry Chemistry Organocatalysis Enantioselective synthesis General Medicine General Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry Catalysis 0104 chemical sciences Stereocenter
Zdroj:	Angewandte Chemie (International ed. in English). 59(2)
ISSN:	1521-3773
Popis:	The enantioselective dearomatization of indoles by an organocatalytic (3+2) reaction has been established. The reaction makes use of simple indole derivatives as substrates, and employs azoalkenes reaction partners. A wide range of pyrroloindolines containing an all-carbon quaternary stereogenic center were readily prepared in high yields and with excellent enantioselectivities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940b7fcc0d0feee43a568513b09bbaae https://pubmed.ncbi.nlm.nih.gov/31592562 Zobrazit plný text záznamu Plný text