Relationship between salivary immunoglobulin a, lactoferrin and lysozyme flow rates and lifestyle factors in Japanese children: a cross-sectional study
| Autor: | Yuko Yamamoto, Masahiro Sugimoto, Keiichi Tsukinoki, Momo Ide, Shinya Fuchida, Mina Yokoyama, Masahiro To, Shigenari Kimoto, Juri Saruta |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Immunoglobulin A Male Saliva Adolescent Cross-sectional study Oral Health 03 medical and health sciences chemistry.chemical_compound fluids and secretions 0302 clinical medicine stomatognathic system Anti-Infective Agents Humans Salivary Proteins and Peptides Child General Dentistry Life Style Salivary immunoglobulin A biology Lactoferrin Body Weight Age Factors 030206 dentistry General Medicine Feeding Behavior Antimicrobial Body Height stomatognathic diseases 030104 developmental biology Lifestyle factors Cross-Sectional Studies chemistry Child Preschool Immunology Immunoglobulin A Secretory biology.protein Female Muramidase Lysozyme Secretory Rate Sleep |
| Zdroj: | Acta odontologica Scandinavica. 74(7) |
| ISSN: | 1502-3850 |
| Popis: | The antimicrobial substances in saliva contribute to the maintenance of both oral health and overall health of the body. Therefore, the associations among immunoglobulin A (IgA), lactoferrin and lysozyme flow rates in the saliva of children, and their relationships with the physical attributes and lifestyle factors of children, were examined.Saliva was collected from 90 children who visited the Kanagawa Dental University Hospital Pediatric Dentistry, and questionnaires were completed by guardians. IgA, lactoferrin and lysozyme concentrations were measured in the saliva samples using enzyme-linked immunosorbent assays (ELISAs).The IgA flow rate in saliva increased as age, height and weight increased. A correlation was found between lactoferrin and lysozyme flow rates. When the antimicrobial substance flow rates in the saliva were divided into two groups of 22 children each based on the highest and lowest quartiles, children with either a low or high IgA flow rate also had a high or low lactoferrin flow rate, respectively. The same pattern was observed for lactoferrin and lysozyme flow rates.There is a high probability that the IgA flow rate in the saliva of children reflects and corresponds to the developmental status of immune function as the child ages and increases in height and weight. The flow rates of lactoferrin and lysozyme were correlated in children. In addition, regarding lifestyle factors, the duration of sleep and lactoferrin flow rate were also related. |
| Databáze: | OpenAIRE |
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