Initial setting of high-flow nasal oxygen post extubation based on mean inspiratory flow during a spontaneous breathing trial
| Autor: | Corrado Liperi, Sophia Butt, Nicholas A Barrett, Leda Floris, Salvatore Grasso, Luigi Camporotaa, Francesco Vasques, Manu Shankar-Hari, Guy Glover, Laura Pistidda, Barnaby Sanderson |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
business.industry
Oxygen Inhalation Therapy Critical Care and Intensive Care Medicine medicine.disease_cause Spontaneous breathing trial Oxygen Inspiratory flow Fraction of inspired oxygen Intensive care Anesthesia Significant positive correlation Airway Extubation Medicine Cannula Humans business High flow Nasal cannula Ventilator Weaning Oxygen saturation (medicine) Retrospective Studies |
| Zdroj: | Journal of critical care. 63 |
| ISSN: | 1557-8615 |
| Popis: | Purpose High flow nasal cannula (HFNC) is commonly used post-extubation in intensive care (ICU). Patients' comfort during HFNC is affected by flow rate. The study aims to describe the relationship between pre-extubation inspiratory flow requirements and the post-extubation flow rates on HFNC that maximises patient's comfort. Methods This was an observational, retrospective study conducted in a university-affiliated ICU. We included patients extubated following successful spontaneous breathing trial (SBT). During the SBT we recorded variables including inspiratory flow. Patients who passed the SBT were extubated onto HFNC. HFNC was titrated from 20 L/min and increased in steps of 10 L/min, up to 60 L/min. At each step, patient's level of comfort was assessed. Fraction of inspired oxygen was titrated to maintain oxygen saturation 92–97%. Results Nineteen participants were enrolled in the study. There was a significant positive correlation between mean inspiratory flow pre-extubation and the flow setting on HFNC which achieved the best comfort post-extubation (r2 0.88; p Conclusion Measuring mean inspiratory flow during an SBT allows for individualised setting of HFNC flow rate immediately post-extubation and achieves the greatest comfort and interface tolerance. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect