Angiosonography in suspicious breast lesions with non-diagnostic FNAC: comparison with power Doppler US
| Autor: | R. Pozzi Mucelli, Mirko D'Onofrio, L. Pinali, F. Caumo, A. Casarin, Simone Vasori, Giovanni Carbognin |
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| Jazyk: | italština |
| Rok vydání: | 2006 |
| Předmět: |
Adult
medicine.medical_specialty Biopsy Fine-Needle Contrast Media Breast Neoplasms Sensitivity and Specificity Breast neoplastic lesions Breast focal lesions Power Doppler US Angiosonography Power doppler symbols.namesake Double-Blind Method Biopsy Humans Medicine Colour doppler ultrasound Radiology Nuclear Medicine and imaging Ultrasonography Doppler Color Aged Neuroradiology Neovascularization Pathologic medicine.diagnostic_test business.industry Ultrasound Interventional radiology General Medicine Middle Aged Aspiration cytology symbols Female Radiology business Doppler effect |
| Popis: | The purpose of this study was to evaluate the accuracy of angiosonography in comparison with colour Doppler ultrasound (US) in the discrimination of suspicious breast lesions with nondiagnostic fine-needle aspiration cytology (FNAC). Pre-operative Power Doppler US and angiosonography were prospectively performed in 20 suspicious breast lesions with non-diagnostic FNAC. A second-generation US contrast agent was utilised with a high-frequency transducer and a contrast-specific algorithm (low acoustic pressure CnTI). The enhancement characteristics of all lesions were analysed using qualitative and quantitative parameters obtained from timeintensity curves with the different imaging modalities. The final diagnosis was confirmed at pathology in all cases. Microvessel density (MVD) was assessed in the surgical specimen using CD34. The correct assessment of biological behaviour was achieved in all cases by angiosonography (sensitivity of 100%; specificity of 91%) and colour Doppler US (45% sensitivity; 78% specificity). MVD correlated with the biological behaviour. Angiosonography is more accurate than colour Doppler US in the correct assessment of biological behaviour of suspicious breast lesions. |
| Databáze: | OpenAIRE |
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