Calcium influx through TRPV4 channels involve in hyperosmotic stress-induced epithelial-mesenchymal transition in tubular epithelial cells

Autor:	Takashi Miyano, Atsushi Suzuki, Naoya Sakamoto
Rok vydání:	2022
Předmět:	Epithelial-Mesenchymal Transition Transient Receptor Potential Channels Biophysics Animals TRPV Cation Channels Calcium Epithelial Cells Cell Biology Cadherins Molecular Biology Biochemistry Rats
Zdroj:	Biochemical and Biophysical Research Communications. 617:48-54
ISSN:	0006-291X
DOI:	10.1016/j.bbrc.2022.06.003
Popis:	The epithelial-mesenchymal transition (EMT) is a biological process that occurs in the pathogenesis of kidney diseases in which injured tubular epithelial cells transform into myofibroblasts. We previously showed that mannitol-mediated hyperosmotic stress induces EMT of tubular epithelial cells. Although Ca
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94047d616a240c4880e1ed9f1f289cec https://doi.org/10.1016/j.bbrc.2022.06.003 Zobrazit plný text záznamu Full Text from ScienceDirect