Differential diagnosis of postoperative liver failure in a 12-year-old child
| Autor: | R. Hausmann, P. Betz, B. Schellmann, B. Schmidt |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Fulminant medicine.medical_treatment Pathology and Forensic Medicine Diagnosis Differential Enflurane Postoperative Complications Fulminant hepatic failure Blood plasma medicine Humans Child Acetaminophen Tonsillectomy business.industry Liver failure Drug Synergism Analgesics Non-Narcotic Hepatitis G Surgery Liver Hepatic Encephalopathy Anesthetics Inhalation Female Chemical and Drug Induced Liver Injury Differential diagnosis business medicine.drug |
| Zdroj: | International Journal of Legal Medicine. 109:210-212 |
| ISSN: | 1437-1596 0937-9827 |
| DOI: | 10.1007/bf01225520 |
| Popis: | The case of a 12-year-old child who died of fulminant hepatic failure a few days after tonsillectomy is reported. Histological examination revealed large areas of massive centrilobular hepatic necrosis. Hepatotoxicity of postoperatively administered paracetamol in high dosages combined with enflurane exposure is discussed as a cause for the hepatic failure. The fulminant clinical course could have been influenced by an infection with hepatitis G virus which was detected in liver tissue by in situ hybridisation and was probably transmitted via transfusion of blood plasma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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