Transient coagulation abnormalities after incompatible blood transfusion
| Autor: | McKenna Pj, Harold Z. Scheinman |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Adult
Male Time Factors medicine.medical_treatment Urination Blood Donors Hemoglobinuria Kinins Critical Care and Intensive Care Medicine Group A ABO Blood-Group System Fibrinolysis medicine Humans Mannitol Whole blood Skin Tests business.industry Fibrinogen Plasmapheresis Kinin Hypofibrinogenemia Blood Coagulation Disorders Blood Coagulation Factors Blood Cell Count Coagulation Hematocrit Blood Group Incompatibility Immunology Incompatible blood transfusion Hemoglobinometry Blood Coagulation Tests business |
| Zdroj: | Critical care medicine. 3(1) |
| ISSN: | 0090-3493 |
| Popis: | This report describes an unusual hemolytic transfusion reaction. A group O donor was inadvertently transfused with 100 ml of group A red cells during the course of plasmapheresis. Granulocytopenia, thrombocytopenia, hypofibrinogenemia and low levels of factors V, VIII, and IX developed immediately after the infusion. The levels of the cellular elements and coagulation proteins returned to normal in less than an hour; too rapid for a de novo synthesis after consumption of coagulation proteins. We postulate that activation of the kinin system was responsible for the phenomena rather than intravascular coagulation with secondary fibrinolysis. |
| Databáze: | OpenAIRE |
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