Hyperammonemic encephalopathy related to valproate, phenobarbital, and topiramate synergism
| Autor: | Elena Urrestarazu-Bolumburu, Asier Gómez-Ibáñez, Cesar Viteri-Torres |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Topiramate
Encephalopathy Fructose Electroencephalography Lesion Behavioral Neuroscience Epilepsy Pharmacotherapy medicine Humans Hyperammonemia Valproic Acid medicine.diagnostic_test business.industry Drug Synergism Middle Aged medicine.disease Neurology Anesthesia Phenobarbital Drug Therapy Combination Female Neurotoxicity Syndromes Neurology (clinical) medicine.symptom business medicine.drug |
| Zdroj: | Epilepsybehavior : EB. 21(4) |
| ISSN: | 1525-5069 |
| Popis: | We present a woman with epilepsy secondary to a lesion in the left frontal lobe. She developed episodes of disorientation and behavioral changes. She was taking valproic acid (1500 mg/day), topiramate (200 mg/day), and phenobarbital (100 mg/day). During an episode, the EEG revealed moderate encephalopathy and ammonia levels were increased (195 μg/dL, reference range: 11-60 μg/dL). Episodes ceased after withdrawal of valproic acid. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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