The role of climbing and parallel fibers inputs to cerebellar cortex in navigation
| Autor: | Laure Rondi-Reig, Jean Caston, Jean Mariani, Nathalie Le Marec |
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| Rok vydání: | 2002 |
| Předmět: |
Male
Brain Mapping Cerebellum Computer science Rats Inbred Strains Rats Task (project management) Lesion Cerebellar Cortex Behavioral Neuroscience Nerve Fibers medicine.anatomical_structure Escape Reaction Motor Skills Orientation Climbing Cerebellar cortex medicine Animals medicine.symptom Maze Learning Neuroscience Psychomotor Performance |
| Zdroj: | Behavioural Brain Research. 132:11-18 |
| ISSN: | 0166-4328 |
| Popis: | DA-HAN rats with partial or total lesion of climbing (CF) and parallel fibers (PF) inputs of the cerebellum were tested in a water task. Two different protocols were used, requiring to find either a non-visible or a visible platform. These two protocols were, respectively, designed to evaluate visuo-motor guidance (visible platform) and navigation (non-visible platform). Both groups of lesioned rats presented a deficit in the non-visible platform task but not in the visible platform one. The protocol of navigation we used was a fixed start–fixed arrival procedure. Totally lesioned animals were unable to learn to orient their body toward the non-visible platform and adopted instead a circling behavior. Our results suggest a role of cerebellar inputs (climbing (CF) and PF) in navigation. |
| Databáze: | OpenAIRE |
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