Effects of age-dependent or liposome-induced alterations in the phospholipid composition on sphingomyelin biosynthesis in rat liver microsomal and plasma membranes
| Autor: | Mariana N. Nikolova, Kamen Koumanov, Diana H. Petkova, Svetlana E. Kochlukova |
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| Rok vydání: | 1991 |
| Předmět: |
Male
Aging Phospholipid Transferases (Other Substituted Phosphate Groups) Biology Biochemistry chemistry.chemical_compound Phosphatidylcholine Animals Phospholipids Phosphatidylethanolamine Liposome Cell Membrane Phosphotransferases Rats Inbred Strains Biological membrane Intracellular Membranes Phosphatidylserine Rats Sphingomyelins carbohydrates (lipids) Membrane chemistry Liposomes Microsomes Liver lipids (amino acids peptides and proteins) Sphingomyelin |
| Zdroj: | International Journal of Biochemistry. 23:689-693 |
| ISSN: | 0020-711X |
| DOI: | 10.1016/0020-711x(91)90039-p |
| Popis: | 1. The effects of age-dependent or liposome-induced alterations in the phospholipid composition of rat liver plasma and microsomal membranes on the phosphatidylethanolamine:ceramide-phosphoethanolamine (PE:Cer-PEt) and phosphatidylcholine:ceramide-phosphocholine (PC:Cer-PCh) transferase activities were studied. 2. In all cases under study the PE:Cer-PEt transferase activity was found to be several times higher than that of PC:Cer-PCh transferase in both plasma and microsomal rat liver membranes. 3. The presence of phosphatidylethanolamine (PE) and phosphatidylglycerol (PG) in plasma membranes was observed to enhance the PE:Cer-PEt transferase activity, while phosphatidylserine (PS) inhibited it. |
| Databáze: | OpenAIRE |
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