Alcohol and brain damage
| Autor: | O. E. Pratt, George K. Shaw, Marina D. Jeyasingham, Allan D. Thomson |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Vitamin
Pathology medicine.medical_specialty Necrosis Alcohol Drinking Health Toxicology and Mutagenesis Physiology Alcohol Brain damage Toxicology Blood–brain barrier 030218 nuclear medicine & medical imaging 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Pregnancy medicine Humans Liver Diseases Alcoholic Ethanol business.industry Thiamine Deficiency Alcoholism medicine.anatomical_structure chemistry Blood-Brain Barrier Fetal Alcohol Spectrum Disorders Toxicity Alcohol intake Thiamine Brain Damage Chronic Female medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Human toxicology. 7(5) |
| ISSN: | 0144-5952 |
| Popis: | The safe limits of alcohol intake are difficult to define because of individual variations in susceptibility to damage. The present recommendations are based largely on epidemiological studies of liver damage. Recent investigations indicate that alcoholic brain damage is much more common than previously suspected. More information is required about its natural history and the characteristics of individuals most likely to suffer damage. Thiamin (vitamin B 1) deficiency has long been associated with brain damage and may result from a number of additive causes in the alcoholic patient. New information indicating damage to the protein moeity of some of the thiamin-using enzymes has been reviewed, as have possible mechanisms of brain cell necrosis. |
| Databáze: | OpenAIRE |
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