Contrast-enhanced MR imaging of the breast: comparison of two different doses of gadopentetate dimeglumine
| Autor: | Sylvia H. Heywang-Köbrunner, R. Beck, M. Untch, J. Haustein, C. Pohl, B. Lommatzsch, W. B. J. Nathrath |
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| Rok vydání: | 1994 |
| Předmět: |
Gadolinium DTPA
medicine.medical_specialty media_common.quotation_subject Contrast Media Breast Neoplasms Group comparison Body weight Breast Diseases Meglumine Organometallic Compounds medicine Humans Contrast (vision) Radiology Nuclear Medicine and imaging Breast Fibrocystic Breast Disease media_common medicine.diagnostic_test business.industry Dose comparison Carcinoma Magnetic resonance imaging Pentetic Acid Image Enhancement Magnetic Resonance Imaging Mr imaging Drug Combinations Fibroadenoma Female Radiology Nuclear medicine business |
| Zdroj: | Radiology. 191:639-646 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/radiology.191.3.8184040 |
| Popis: | PURPOSE: To optimize detection and diagnosis of breast lesions with contrast-enhanced magnetic resonance (MR) imaging. MATERIALS AND METHODS: A three-dimensional fast low-angle shot pulse sequence was used for a group comparison consisting of 76 high-dose (0.16 mmol gadopentetate dimeglumine per kilogram of body weight) and 76 low-dose (0.1 mmol/kg) examinations. Intraindividual comparisons were possible in a subgroup of 20 patients. RESULTS: Enhancement with the high dose was about 1.5 times higher for benign and malignant tissues. With the lower dose, no false-positive findings could be avoided and definition of a threshold that excluded false-negative findings was problematic. Conspicuity of malignant lesions was much improved with the higher dose (a good to excellent rating in 81% vs 26% with the lower dose). Three small foci were visible only with the higher dose. CONCLUSION: The higher dose of contrast material allowed much better results. Dose comparison studies are also recommended for other techn... |
| Databáze: | OpenAIRE |
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