Swine enteric alphacoronavirus (swine acute diarrhea syndrome coronavirus): an update three years after its discovery
| Autor: | Yao-Wei Huang, Jia Qi Yu, Yong-Le Yang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Cancer Research
China swine enteric alphacoronavirus (SeACoV) Swine diagnosis viruses etiology Genome Viral Biology medicine.disease_cause Alphacoronavirus Virus Article Cell Line 03 medical and health sciences Species Specificity Virology medicine Animals Humans pathogenicity Epizootic Tropism 030304 developmental biology Coronavirus Swine Diseases 0303 health sciences Molecular Epidemiology Molecular epidemiology 030306 microbiology Transmission (medicine) transmission virus diseases respiratory system biochemical phenomena metabolism and nutrition biology.organism_classification medicine.disease swine acute diarrhea syndrome coronavirus (SADS-CoV) respiratory tract diseases Viral Tropism Infectious Diseases Tissue tropism Coronavirus Infections |
| Zdroj: | Virus Research |
| ISSN: | 1872-7492 0168-1702 |
| Popis: | Highlights • A summary of the research progress in SeACoV (SADS-CoV) from 2017-2020. • Bat-derived SeACoV was most recently recognized prior to SARS-CoV-2 associated with COVID-19. • Focusing on the etiology, epidemiology, evolutionary perspective, potential for interspecies transmission, pathogenesis and diagnosis. Discovered in 2017, swine enteric alphacoronavirus (SeACoV), also known as swine acute diarrhea syndrome coronavirus (SADS-CoV) or porcine enteric alphacoronavirus (PEAV), is the fifth porcine CoV identified in diarrheal piglets. The presumed name “SADS-CoV” may not be appropriate since current studies have not provided strong evidence for high pathogenicity of the virus. SeACoV was the most recently recognized CoV of potential bat origin prior to the novel human severe acute respiratory syndrome CoV 2 (SARS-CoV-2), associated with the pandemic CoV disease 2019 (COVID-19). Although SeACoV is recognized as a regional epizootic virus currently, it possesses the most extensive cell species tropism in vitro among known CoVs. This review summarizes the emergence of SeACoV and updates the research progress made from 2017 to early 2020, mainly focusing on the etiology, epidemiology, evolutionary perspective, potential for interspecies transmission, pathogenesis and diagnosis. |
| Databáze: | OpenAIRE |
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