Popis: |
Table S1: relevant clinical trials investigating targeted therapies for T-ALL treatment: List of clinical trials investigating the targeted agents described in this review. The clinical trials listed were chosen based on the following two selection criteria: the targeted drug investigated belongs to one of the categories of agents described in the text (modifiers of apoptosis, inhibitors of transcription regulation, signal transduction, cell cycle or immunotherapies) and the trial includes T-ALL patients. * Source: https://clinicaltrials.gov/ Abbreviations: p= pediatric, ya= young adult, a= adults; ALL= acute lymphoblastic leukemia, LBL= lymphoblastic lymphoma, AML= acute myeloid leukemia, MDS= myelodysplastic syndrome, MM= multiple myeloma, Dx= newly diagnosed, R/R= refractory/relapsed; chemo= chemotherapy; dexa= dexamethasone; WT= wild-type; N/A= not applicable, R= recruiting, A= active, C= completed, T= terminated, NR= not yet recruiting. |