Longitudinal changes to quadriceps thickness demonstrate acute sarcopenia following admission to hospital for an exacerbation of chronic respiratory disease
| Autor: | Matthew Richardson, Neil J. Greening, Theresa Harvey-Dunstan, Michael C Steiner, Michelle Craner, Sally Singh, Hamish McAuley |
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| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male Sarcopenia Exacerbation medicine.medical_treatment Quadriceps Muscle Patient Admission Quality of life Risk Factors Medicine Humans Pulmonary rehabilitation Aged Retrospective Studies business.industry Surrogate endpoint Respiratory disease Retrospective cohort study medicine.disease Prognosis Respiration Disorders Anesthesia Hospital admission Chronic Disease Disease Progression Quality of Life Female business Follow-Up Studies |
| Zdroj: | Thorax. 76(7) |
| ISSN: | 1468-3296 |
| Popis: | Acute admission to hospital for an exacerbation of chronic respiratory disease (CRD) may impair skeletal muscle mass and function. We measured quadriceps thickness (Qthick), as a surrogate marker of muscle mass, at hospital admission, discharge, 6 weeks and 3 months in 55 patients with CRD. Qthick fell by 8.3% during the period of hospitalisation, which was sustained at 6 weeks, and only partially recovered at 3 months. Sustained loss was most marked in patients readmitted during the follow-up period. Acute reduction in quadriceps muscle mass occurs during hospitalisation, with prolonged and variable recovery, which is prevented with subsequent hospital readmission. |
| Databáze: | OpenAIRE |
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