Niveles de hormonas tiroideas en niños obesos
| Autor: | Trinidad Sánchez B, Hernán García B, Jaime Godoy S, Salesa Barja Y |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
endocrine system
Pediatrics medicine.medical_specialty Waist endocrine system diseases business.industry Overweight medicine.disease Obesity Endocrinology Thyroid-stimulating hormone pediatría Internal medicine Pediatrics Perinatology and Child Health Medicine Euthyroid Thyroid function medicine.symptom Tiroides business obesidad Body mass index hormones hormone substitutes and hormone antagonists hipotiroidismo Subclinical infection |
| Zdroj: | Revista chilena de pediatría v.85 n.3 2014 SciELO Chile CONICYT Chile instacron:CONICYT |
| ISSN: | 0370-4106 |
| DOI: | 10.4067/s0370-41062014000300004 |
| Popis: | Introduction: Study results regarding thyroid function in obese children are unknown. The objective of this study was to describe the levels of thyroid stimulating hormone (TSH), free plasma thyroxine (FT4), associated factors and frequency of hypothyroidism in these children. Patients and Method: A retrospective study of medical records of 260 obese children who consulted a physician for the first time between January 2007 and June 2012. Age, gender, puberty, weight, height and waist circumference (WC) were considered; body mass index (BMI z -score), weight/height (IPT) and height/age (NCHS 2000) were calculated, and TSH and FT4 were measured. Results: 210 patients aged 2 to 18 years were included, 59% female, 51.4% prepubescent children, 23.9% were overweight and 76.1% obese. 70.8% of the children surveyed had central obesity. TSH and FT4 values were 2.31 μUI/mL (0.69 to 8.07) and 1.289 ± 0.17 ng/dL, respectively. Hypothyroidism was found in 21 patients (10%), 20 of these presented it as subclinical condition. An inverse correlation was present between age and log TSH and a direct correlation was described between log TSH and zBMI. Qnly zBMI was significant (p < 0.001, adjusted R2 8.2%, β 0.19) after using multiple regression. No differences in age, gender, nutritional status and puberty between euthyroid and hypothyroid patients were found. Conclusion: 9.5% of patients presented subclinical hypothyroidism, which supports TSH screening in obese children. |
| Databáze: | OpenAIRE |
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