Impact of adjuvant taxane-based chemotherapy on development of breast cancer-related lymphedema: results from a large prospective cohort

Autor:	Cynthia L. Miller, Jean O’Toole, Chantal M. Ferguson, Melissa N. Skolny, Meyha N. Swaroop, Cheryl L. Brunelle, Nora Horick, Lauren S. Jammallo, Alphonse G. Taghian, Steven J. Isakoff, Michelle C. Specht
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	Oncology Quality of life Adult Bridged-Ring Compounds Cancer Research medicine.medical_specialty Time Factors medicine.medical_treatment Breast Neoplasms 03 medical and health sciences Young Adult 0302 clinical medicine Breast cancer Internal medicine Taxane chemotherapy Antineoplastic Combined Chemotherapy Protocols medicine Humans Cumulative incidence 030212 general & internal medicine Lymphedema Prospective cohort study Mastectomy Aged 2. Zero hunger Aged 80 and over Chemotherapy Taxane business.industry Incidence Middle Aged medicine.disease Arm swelling Clinical Trial 3. Good health Docetaxel Chemotherapy Adjuvant 030220 oncology & carcinogenesis Female Taxoids business medicine.drug Follow-Up Studies
Zdroj:	Breast Cancer Research and Treatment
ISSN:	1573-7217 0167-6806
Popis:	Taxane-based chemotherapy for the treatment of breast cancer is associated with fluid retention in the extremities; however, its association with development of breast cancer-related lymphedema is unclear. We sought to determine if adjuvant taxane-based chemotherapy increased risk of lymphedema or mild swelling of the upper extremity. 1121 patients with unilateral breast cancer were prospectively screened for lymphedema with perometer measurements. Lymphedema was defined as a relative volume change (RVC) of ≥10 % from preoperative baseline. Mild swelling was defined as RVC 5
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e08100a6962f6658914473c502423e http://europepmc.org/articles/PMC4432026 Zobrazit plný text záznamu Full text from SpringerLink