Biocompatibility of new calcium aluminate cement (EndoBinder)
| Autor: | Lucas da Fonseca Roberti Garcia, Fernanda de Carvalho Panzeri Pires-de-Souza, F. G. Aguilar |
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| Rok vydání: | 2011 |
| Předmět: |
Mineral trioxide aggregate
Male Materials science Necrosis Time Factors Biocompatibility Neutrophils Plasma Cells Connective tissue chemistry.chemical_element Neovascularization Physiologic Biocompatible Materials Calcium Giant Cells SILICATOS (FARMACOLOGIA) Andrology Root Canal Filling Materials Subcutaneous Tissue Edema Materials Testing medicine Animals Lymphocytes Rats Wistar Aluminum Compounds General Dentistry Cement Inflammation Phagocytes Macrophages Silicates Oxides Calcium Compounds Fibroblasts Rats Drug Combinations medicine.anatomical_structure chemistry Connective Tissue Polyethylene Microvessels Leukocytes Mononuclear Collagen medicine.symptom Intubation Subcutaneous tissue |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| ISSN: | 1878-3554 |
| Popis: | Introduction The purpose of this study was to evaluate the biocompatibility of calcium aluminate cement (EndoBinder) in subcutaneous tissue of rats. Methods Fifteen rats, weighing 300 g, were separated into 3 groups (n = 5) in accordance with the time of death (7, 21, 42 days). Two incisions were made in the dorsal subcutaneous tissue of each rat in which were implanted 2 polyethylene tubes filled with the test materials, EndoBinder (EB) and Grey MTA (GMTA). The external tube walls were considered the negative control group (CG). After 7, 21, and 42 days, animals were killed, obtaining 5 samples per group, at each time interval of analysis. Results From the morphologic and morphometric analyses by using a score of (0–3) (50, 100, and 400×), results showed absence of inflammatory reaction (0) for EB after 42 days. However, for GMTA, a slight inflammatory reaction (1) was observed after 42 days, which means the persistence of a chronic inflammatory process. When compared with CG, tissue reaction ranging from discrete (1–7 days) to absent (0–42 days) was observed. Conclusions EndoBinder presented satisfactory tissue reaction; it was biocompatible when tested in subcutaneous tissue of rats. |
| Databáze: | OpenAIRE |
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