Seizure Recurrence in Children after Stopping Antiepileptic Medication: 5-Year Follow-Up
| Autor: | Yung-Jung Chen, Inn-Chi Lee, Shuan-Yow Li |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty recurrence 5 year follow up Multivariate analysis Adolescent Status epilepticus Seizure recurrence 03 medical and health sciences Epilepsy Status Epilepticus antiepileptic drug remission 0302 clinical medicine children Risk Factors Seizures Humans Medicine Pediatrics Perinatology and Child Health 030212 general & internal medicine Child Univariate analysis business.industry lcsh:RJ1-570 Electroencephalography lcsh:Pediatrics medicine.disease Predictive factor Child Preschool Anesthesia Multivariate Analysis Pediatrics Perinatology and Child Health outcome Etiology epilepsy Anticonvulsants Female medicine.symptom business 030217 neurology & neurosurgery Follow-Up Studies |
| Zdroj: | Pediatrics and Neonatology, Vol 58, Iss 4, Pp 338-343 (2017) |
| ISSN: | 1875-9572 |
| Popis: | Background We wanted to identify in children with epilepsy the factors associated with seizure control and recurrence after a 2-year remission. Methods We did a 5-year follow-up of epileptic children whose antiepileptic medication had been stopped. Bivariate and multivariate analyses were used to compare features of electroencephalograms (EEGs) and clinical findings. In this study, 43 patients with and 64 without a seizure recurrence (SR) were enrolled. Results Clinical features strongly associated with SR in the univariate analysis included a symptomatic etiology for seizures, a history of status epilepticus, treatment duration before stopping antiepileptic drugs, and abnormal EEG findings at the time of stopping antiepileptic drugs. Conclusion We found that a history of status epilepticus, symptomatic partial epilepsy, treatment duration before stopping antiepileptic drugs, and an abnormal EEG when the medication was stopped are important predictors of SR. The risk factors of SR after discontinuing antiepileptic drugs have been investigated in several studies. However, a history of status epilepticus as a predictive factor is rarely mentioned. |
| Databáze: | OpenAIRE |
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