Prospective study of healthcare utilisation and respiratory morbidity due to RSV infection in prematurely born infants
| Autor: | Simon Broughton, Mark Zuckerman, Anne Greenough, Elena Pollina, Grenville F. Fox, Alison Roberts, Shenila Chaudhry |
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| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Pediatrics medicine.medical_specialty Paediatric Lung Disease Denmark viruses Infant Premature Diseases Respiratory Syncytial Virus Infections Risk Factors Wheeze Epidemiology medicine Humans Community Health Services Prospective Studies Letters to the Editor Prospective cohort study Respiratory Tract Infections Pregnancy Respiratory tract infections business.industry Respiratory disease Infant Newborn Gestational age virus diseases Patient Acceptance of Health Care respiratory system medicine.disease respiratory tract diseases Hospitalization medicine.anatomical_structure Regression Analysis Female medicine.symptom Family Practice business Respiratory tract |
| Popis: | Background: A study was undertaken to determine the impact of respiratory syncytial virus (RSV) infection, both in hospital and the community, on healthcare utilisation and respiratory morbidity in prematurely born infants and to identify risk factors for symptomatic RSV infection. Methods: A hospital and community follow up study was undertaken of 126 infants born before 32 weeks of gestational age. Healthcare utilisation (hospital admissions and general practitioner attendances) in the first year, respiratory morbidity at follow up (wheeze and cough documented by parent completed diary cards), and RSV positive lower respiratory tract infections (LRTIs) were documented. Nasopharyngeal aspirates were obtained for immunofluorescence and culture for RSV whenever the infants had an LRTI, either in the community or in hospital. Results: Forty two infants had an RSV positive LRTI (RSV group), 50 had an RSV negative LRTI (RSV negative LRTI group), and 32 infants had no LRTI (no LRTI group). Compared with the RSV negative LRTI and the no LRTI groups, the RSV group required more admissions (p = 0.392, p |
| Databáze: | OpenAIRE |
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