Prospective analysis of psychological differences between adult and elderly cancer patients during postoperative adjuvant chemotherapy

Autor: Beatriz Castelo, Jacobo Rogado, M. C. Soriano-Rodríguez, Carlos Jara, Carmen Beato, Raquel Hernández, Montserrat Mangas-Izquierdo, Alberto Carmona-Bayonas, Teresa García-García, Caterina Calderon, Paula Jiménez-Fonseca, M. M. Muñoz-Sánchez
Rok vydání: 2018
Předmět:
Male
Cancer Research
Pediatrics
Coping (psychology)
Adjuvant chemotherapy
medicine.medical_treatment
Psychological intervention
Persones grans
Elderly
0302 clinical medicine
Neoplasms
Adaptation
Psychological
Antineoplastic Combined Chemotherapy Protocols
Postoperative Period
Prospective Studies
030212 general & internal medicine
Càncer
Prospective cohort study
Cancer
education.field_of_study
Age Factors
General Medicine
Middle Aged
Adulthood
Oncology
Chemotherapy
Adjuvant
030220 oncology & carcinogenesis
Female
Cancer chemotherapy
Coping
Adjuvant
Quality of life
Adult
medicine.medical_specialty
Adolescent
Population
Young Adult
Quimioteràpia del càncer
03 medical and health sciences
Social support
Psychological adaptation
medicine
Humans
Adults
education
Shared decision-making
Aged
Diferències individuals
business.industry
Cross-Sectional Studies
Individual differences
Quality of Life
Older people
business
Zdroj: Dipòsit Digital de la UB
Universidad de Barcelona
ISSN: 1699-3055
1699-048X
Popis: PURPOSE: Despite the burgeoning geriatric population with cancer and the importance of understanding how age may be related to mental adjustment and quality of life so far, differences in coping strategies and psychological harm between the elderly and adults are hardly being taken into account to modify the approach to this population. The aim of this prospective study is to describe the differences in psychological characteristics between older and adult cancer patients and examine dissimilarities in their psychological evolution during adjuvant chemotherapy. METHODS: Adults (18-69 years old) and older patients (≥ 70) with newly diagnosed non-metastatic resected cancer admitted to receive adjuvant chemotherapy were recruited. Patients completed the following questionnaires: mini-mental adjustment to cancer, brief symptom inventory, shared decision-making questionnaire-patient's version, multidimensional scale of perceived social support, EORTC quality-of-life instrument, life orientation test-revised, and satisfaction with life scale. RESULTS: 500 cancer patients (394 adults and 106 older) were evaluated. The impact of the diagnosis was less negative among older patients, with no differences in coping strategies, quality of life, or search for support. Regarding psychological changes from the beginning to the end of the adjuvant treatment, both age groups reported more somatic symptoms, increased psychological difficulty, reduced coping strategies, and a significant decrease in quality of life at the end of postoperative chemotherapy. CONCLUSION: Although there were clear psychological differences between adults and senior cancer patients, their evolution during adjuvant chemotherapy was similar, with deterioration in quality of life and coping. This negative psychological impact of adjuvant chemotherapy should be taken into account when considering interventions.
Databáze: OpenAIRE
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