Botanical drugs and supplements affecting the immune response in the time of COVID-19: Implications for research and clinical practice
| Autor: | Mary L. Hardy, Elizabeth Williamson, Michael Heinrich, Hossein Hosseinzadeh, Stefan Gafner, Alexander Panossian, Thomas Brendler, Solomon P. Wasser, Ahmed Al-Harrasi, Marjan Nassiri-Asl, Rudolf Bauer, Angelo A. Izzo, Martin Michaelis |
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| Přispěvatelé: | Brendler, T., Al-Harrasi, A., Bauer, R., Gafner, S., Hardy, M. L., Heinrich, M., Hosseinzadeh, H., Izzo, A. A., Michaelis, M., Nassiri-Asl, M., Panossian, A., Wasser, S. P., Williamson, E. M. |
| Rok vydání: | 2020 |
| Předmět: |
media_common.quotation_subject
Disease Pelargonium sidoides Pelargonium medicinal fungi Echinacea law.invention salicylate 03 medical and health sciences 0302 clinical medicine Immune system Curcuma law Pandemic Health care Glycyrrhiza Medicine Humans Boswellia media_common Pharmacology 0303 health sciences Plants Medicinal Traditional medicine biology business.industry SARS-CoV-2 Convalescence 030302 biochemistry & molecular biology Novelty Immunity COVID-19 biology.organism_classification COVID-19 Drug Treatment adaptogen Sambucus 030220 oncology & carcinogenesis herbal medicine Dietary Supplements Plant Preparations business Phytotherapy |
| Zdroj: | Phytotherapy Research |
| ISSN: | 1099-1573 |
| Popis: | In times of health crisis, including the current COVID-19 pandemic, the potential benefit of botanical drugs and supplements emerges as a focus of attention, although controversial efficacy claims are rightly a concern. Phytotherapy has an established role in everyday selfcare and health care, and since botanical preparations contain many chemical constituents rather than single compounds, challenges arise in demonstrating efficacy and safety. However, there is ample traditional, empirical and clinical evidence that botanicals can offer some protection and alleviation of disease symptoms as well as promoting general well-being. Newly emerging viral infections, specifically COVID-19, represent a unique challenge in their novelty and absence of established antiviral treatment or immunization. We discuss here the roles and limitations of phytotherapy in helping to prevent and address viral infections, and specifically regarding their effects on immune response. Botanicals with a documented immunomodulatory, immunostimulatory, and anti-inflammatory effect include adaptogens, Boswellia spp., Curcuma longa, Echinacea spp., Glycyrrhiza spp., medicinal fungi, Pelargonium sidoides, salicylate-yielding herbs, and Sambucus spp. We further provide a clinical perspective on applications and safety of these herbs in prevention, onset, progression, and convalescence from respiratory viral infections. |
| Databáze: | OpenAIRE |
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