VACCINATION OF MONKEYS AND LABORATORY WORKERS AGAINST PSITTACOSIS

Autor:	Thomas M. Rivers, Francis F. Schwentker
Rok vydání:	1934
Předmět:	biology business.industry Immunology medicine.disease Psittacosis Virology Article Neutralization Virus Vaccination Active agent medicine biology.protein Immunology and Allergy Antibody Intramuscular injection business Pneumonia (non-human)
Zdroj:	The Journal of Experimental Medicine
ISSN:	1540-9538 0022-1007
Popis:	Monkeys that have recovered from psittacosis pneumonia have an increased resistance to infection with the virus and possess neutralizing antibodies in their sera. Large amounts of active psittacosis virus can be introduced intravenously and intramuscularly into monkeys without the production of a serious infection such as pneumonia. Relatively small amounts of virus introduced intratracheally into monkeys usually lead to psittacosis pneumonia. Monkeys vaccinated intramuscularly with unattenuated psittacosis virus have an increased resistance to the active agent and possess neutralizing antibodies in their sera. The intramuscular introduction of active psittacosis virus in moderate amounts into human beings is relatively harmless, and repeated inoculations lead to the appearance of neutralizing antibodies in the sera of vaccinated individuals.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b3d735b64f4af3c7ad3992738d840d https://doi.org/10.1084/jem.60.2.211 Zobrazit plný text záznamu